Computational methods for optical molecular imaging

Computational methods for optical molecular imaging.

A new computational technique, the matched interface and boundary (MIB) method, is presented to model the photon propagation in biological tissue for the optical molecular imaging. Optical properties have significant differences in different organs of small animals, resulting in discontinuous coefficients in the diffusion equation model. Complex organ shape of small animal induces singularities...

Computational Methodology of Optical Molecular Imaging

1 Chinese Academy of Sciences, Beijing 100864, China 2 Center for Molecular Imaging, University of Texas Health Science Center at Houston, Houston, TX 77030, USA 3 School of Life Science and Technology, Xidian University, Xi’an, Shaanxi 710071, China 4College of Chemistry, Nankai University, Tianjin 300071, China 5 Department of Radiology, Union Hospital, Chinese Academy of Medical Sciences and...

Computational methods for optical mapping

Optical mapping and newer genome mapping technologies based on nicking enzymes provide low resolution but long-range genomic information. The optical mapping technique has been successfully used for assessing the quality of genome assemblies and for detecting large-scale structural variants and rearrangements that cannot be detected using current paired end sequencing protocols. Here, we review...

Analysis Methods for Optical Imaging

Computational Methods for Microwave Medical Imaging

Medical imaging methods have become increasingly important in diagnosing diseases and assisting therapeutic treatment. In particular, early detection of breast cancer is considered as a critical factor in reducing the mortality rate of women. Within the various alternative breast imaging modalities being investigated to improve breast cancer detection, microwave imaging is attractive due to the...